Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?

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Title: Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?
Authors: Roberto García-Figueiras, Sandra Baleato-González, Anwar R Padhani, Laura Oleaga, Joan C Vilanova, Antonio Luna, Juan Carlos Cobas Gómez
Date: 2016/09/13
Reference: Diagn Interv Radiol 2016; 22: 75-89
DOI: http://dx.doi.org/10.5152/dir.2015.15009
Download link: http://www.dirjournal.org/eng/makale/1415/80/Full-Text

 

ABSTRACT

Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.

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