Mnova Binding – Batch processing mode

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Watch this video about our new product Mnova Binding in batch processing mode!

A powerful tool that automatically processes 2D HSQC type of protein-ligand titration spectra, tracks the peak movement and computes the Kd‘s for multiple peaks also in batch processing mode.

Carries out statistical analysis on Kd‘s of multiple peaks and can also submit the measured CSPs to 3rd party software (AFFINImeter) for advanced analysis of binding isotherms using different binding models.

  • Intuitive workflow that allows you to analyze CSP titration spectra interactively or fully automatically.
  • Automatic peak movement tracking and measurement of chemical shift perturbations (CSPs), fitting them to the concentrations of ligands to compute Kd.
  • Provides tools for processing and stacking multiple 2D HSQC spectra. It displays them in different colors.
  • Corrects the automatic peak movement tracking in crowded spectral areas.
  • Easy exporting of CSP values for further studies of the ligand-protein binding models.

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Enrique Sánchez

Scientific Content Editor in Mestrelab Research S.L. Read his profile here.

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